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Why so many builds?

Different CUDA versions support different hardware (compute capabilites), and different driver versions support different CUDA versions. As such, we need multiple builds to support all the various hardware/software combinations.

Which build do I use?

The one that matches (or is the closest less-than-or-equal-to) the CUDA version supported by your driver.
e.g. Driver supports CUDA 12.1, use the build that targets CUDA 12.0.

To check your driver's CUDA version, run nvidia-smi, which reports the supported CUDA version on the first line (on driver 410.72 and newer¹). If your driver is older than that, consult this table.